Endocrine Abstracts

ObjectiveIn BALB/c mice with GD model, the TSHR and ICAM-1 were targeted for treatment, and new approaches to GD targeted therapy were explored.MethodsThe siRNA targeting TSHR and the ICAM-1 mAb specifically binding ICAM-1 were designed and synthesized. Thirty GD model mice were randomly divided into siRNA treatment group, ICAM-1 mAb treatment group, and untreated GD group, with 10 mice in each group, and 10 ...

Background and aims: Coronary artery disease (CAD) plays an important role in global mortality worldwide. Risk assessment for patients with CAD through free triiodothyronine (FT3) remains unclear. Therefore, we aimed to investigate the impact of FT3 on the prognosis of patients with CAD.Methods: A total of 0 patients with CAD and available FT3 data, and without overt thyroid disease were enrolled in this study and grouped by tertiles. The primary outcome...